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Publicaciones - Metalofármacos antitumorales no convencionales

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Kasparkova J, Novohradsky V, Ruiz J, Brabec V. Photoactivatable, mitochondria targeting dppz iridium(III) complex selectively interacts and damages mitochondrial DNA in cancer cells. Chem Biol Interact. 2024 Apr 1;392:110921. doi: 10.1016/j.cbi.2024.110921. Epub 2024 Feb 19. PubMed PMID: 38382705.
AÑO: 2024; IF: 4.7
38382705
Marco A, Ashoo P, Hernandez-Garcia S, Martinez-Rodriguez P, Cutillas N, Vollrath A, Jordan D, Janiak C, Gandia-Herrero F, Ruiz J. Novel Re(I) Complexes as Potential Selective Theranostic Agents in Cancer Cells and In Vivo in Caenorhabditis elegans Tumoral Strains. J Med Chem. 2024 Mar 7. doi: 10.1021/acs.jmedchem.3c01869. Online ahead of print. PubMed PMID: 38451016.
AÑO: 2024; IF: 6.8
38451016
Kasparkova J, Hernandez-Garcia A, Kostrhunova H, Goicuria M, Novohradsky V, Bautista D, Markova L, Santana MD, Brabec V, Ruiz J. Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis. J Med Chem. 2024 Jan 11;67(1):691-708. doi: 10.1021/acs.jmedchem.3c01978. Epub 2023 Dec 23. PubMed PMID: 38141031; PubMed Central PMCID: PMC10788912.
AÑO: 2024; IF: 6.8
38141031
Ballester FJ, Hernandez-Garcia A, Santana MD, Bautista D, Ashoo P, Ortega-Forte E, Barone G, Ruiz J. Photoactivatable Ruthenium Complexes Containing Minimal Straining Benzothiazolyl-1,2,3-triazole Chelators for Cancer Treatment. Inorg Chem. 2024 Apr 8;63(14):6202-6216. doi: 10.1021/acs.inorgchem.3c04432. Epub 2024 Feb 22. PubMed PMID: 38385171; PubMed Central PMCID: PMC11005040.
AÑO: 2024; IF: 4.3
38385171
Ortega-Forte E, Rovira A, Lopez-Corrales M, Hernandez-Garcia A, Ballester FJ, Izquierdo-Garcia E, Jorda-Redondo M, Bosch M, Nonell S, Santana MD, Ruiz J, Marchan V, Gasser G. A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions. Chem Sci. 2023 Jun 8;14(26):7170-7184. doi: 10.1039/d3sc01844j. eCollection 2023 Jul 5. PubMed PMID: 37416722; PubMed Central PMCID: PMC10321499.
AÑO: 2023; IF: 7.6
37416722
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IMIB-Arrixaca

Instituto de Investigación Sanitaria Acreditado

ISCII

Metalofármacos antitumorales no convencionales