Publicaciones - Metalofármacos antitumorales no convencionales

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Linero-Artiaga A., Servos L.M., Papadopoulos Z., Rodríguez V., Ruiz J., Karges J. Conjugation of a cyclometalated Ir(iii) complex to human serum albumin for oncosis-mediated photodynamic therapy. Inorganic Chemistry Frontiers. 21 November 2025. 12:7068-7082. 10.1039/d5qi01287b

AÑO: 2025; IF: 6.4

Novohradsky V., Marco A., Svitelova M., Cutillas N., Ruiz J., Brabec V. Photoactivatable Cyclometalated Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors. ACS Pharmacology and Translational Science. 11 July 2025. 8:2033-2047. 10.1021/acsptsci.5c00145

AÑO: 2025; IF: 4.0

Vigueras G., Izquierdo-García E., de la Torre-Rubio E., Abad-Montero D., Santana M.D., Marchán V., Ruiz J. Metal-coumarin derivatives as promising photosensitizers: unlocking their cancer phototherapy potential. Inorganic Chemistry Frontiers. 8 May 2025. 12:4355-4375. 10.1039/d5qi00858a

AÑO: 2025; IF: 6.2

Ballester FJ, Hernandez-Garcia A, Santana MD, Bautista D, Ashoo P, Ortega-Forte E, Barone G, Ruiz J. Photoactivatable Ruthenium Complexes Containing Minimal Straining Benzothiazolyl-1,2,3-triazole Chelators for Cancer Treatment. Inorg Chem. 2024 Apr 8;63(14):6202-6216. doi: 10.1021/acs.inorgchem.3c04432. Epub 2024 Feb 22. PubMed PMID: 38385171; PubMed Central PMCID: PMC11005040.

AÑO: 2024; IF: 4.7

38385171

Kasparkova J, Novohradsky V, Ruiz J, Brabec V. Photoactivatable, mitochondria targeting dppz iridium(III) complex selectively interacts and damages mitochondrial DNA in cancer cells. Chem Biol Interact. 2024 Apr 1;392:110921. doi: 10.1016/j.cbi.2024.110921. Epub 2024 Feb 19. PubMed PMID: 38382705.

AÑO: 2024; IF: 5.4

38382705

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Publicaciones - Metalofármacos antitumorales no convencionales

Instituto de Investigación Sanitaria Acreditado

Metalofármacos antitumorales no convencionales