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Publicaciones - Metalofármacos antitumorales no convencionales

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Rovira A, Ortega-Forte E, Hally C, Jorda-Redondo M, Abad-Montero D, Vigueras G, Martinez JI, Bosch M, Nonell S, Ruiz J, Marchan V. Exploring Structure-Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates. J Med Chem. 2023 Jun 22;66(12):7849-7867. doi: 10.1021/acs.jmedchem.3c00189. Epub 2023 Jun 2. PubMed PMID: 37265008; PubMed Central PMCID: PMC10291553.
AÑO: 2023; IF: 6.8
37265008
Marco A, Vigueras G, Busto N, Cutillas N, Bautista D, Ruiz J. Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria. Dalton Trans. 2023 Oct 3;52(38):13482-13486. doi: 10.1039/d3dt01678a. PubMed PMID: 37358044.
AÑO: 2023; IF: 3.5
37358044
Novohradsky V, Marco A, Markova L, Cutillas N, Ruiz J, Brabec V. Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells. J Med Chem. 2023 Jul 27;66(14):9766-9783. doi: 10.1021/acs.jmedchem.3c00586. Epub 2023 Jul 6. PubMed PMID: 37410386; PubMed Central PMCID: PMC10388354.
AÑO: 2023; IF: 6.8
37410386
Hernandez-Garcia A, Markova L, Santana MD, Pracharova J, Bautista D, Kostrhunova H, Novohradsky V, Brabec V, Ruiz J, Kasparkova J. Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis. Inorg Chem. 2023 Apr 24;62(16):6474-6487. doi: 10.1021/acs.inorgchem.3c00501. Epub 2023 Apr 11. PubMed PMID: 37040203; PubMed Central PMCID: PMC10131226.
AÑO: 2023; IF: 4.3
37040203
Ortega-Forte E, Hernandez-Garcia S, Vigueras G, Henarejos-Escudero P, Cutillas N, Ruiz J, Gandia-Herrero F. Potent anticancer activity of a novel iridium metallodrug via oncosis. Cell Mol Life Sci. 2022 Sep 6;79(10):510. doi: 10.1007/s00018-022-04526-5. PubMed PMID: 36066676; PubMed Central PMCID: PMC9448686.
AÑO: 2022; IF: 8.0
36066676
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IMIB-Arrixaca

Instituto de Investigación Sanitaria Acreditado

ISCII

Metalofármacos antitumorales no convencionales